South Asian Journal of Research in Microbiology

Bladder inflammation, commonly brought on by a bladder infection, is known as cystitis. This sort of urinary tract infection (UTI) is widespread, especially in women, and is usually not as significant of a problem as it seems. Bacteria in the lower urinary tract are typically the cause of cystic cystitis. The bacteria Escherichia coli is typically the cause, accounting for 95% of cases. Bacteria can occasionally enter the bladder through the urethra and cause cystitis, an inflammation of the bladder typically brought on by a bladder infection. It's a prevalent kind of urinary tract infection (UTI), especially in women, and typically only causes minor discomfort rather than alarm. When treating women with simple acute cystitis, trimethoprim-sulfamethoxazole (TMP-SMX), fosfomycin, or nitrofurantoin monohydrate/macrocrystals are the first-choice medications. When other suggested medications are not effective, beta-lactam antibiotics may be utilized. 33.54% of people had a UTI, with 66.78% female and 33.22% male. In India, there was a higher frequency in females than in males (2:1). 2019 estimates for the world included 404.61 million cases, 236,790 deaths, and 520,200 DALYs. Specifically, there was a 2.4-fold increase in deaths between 1990 and 2019, and the age-standardized mortality rate (ASMR) went from 2.77/100,000 to 3.13/100,000. In this review study, we discuss the causes, prevalence, available treatments, and current status of cystitis.